|
|
3beta,7alpha,12alpha-trihydroxy-5beta-cholanoate + NAD+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADH + H+
|
1.1.1.391
3beta-hydroxycholanate 3-dehydrogenase (NAD+)
|
–
|
| |
BRENDA:
BS434570
MetaCyc:
RXN-11472
|
|
|
|
3alpha,7alpha,12beta-trihydroxy-5beta-cholanoate + NADP+ <=> 12-ketochenodeoxycholic_acid + NADPH + H+
|
1.1.1.238
12beta-hydroxysteroid dehydrogenase
|
–
|
| |
BRENDA:
BR29274
KEGG:
R03495
MetaCyc:
12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN
|
|
|
|
cholic_acid + NAD+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADH + H+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.395
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.52
3alpha-hydroxycholanate dehydrogenase (NAD+)
|
–
–
–
–
–
|
| |
BRENDA:
BS188316;
BS230636-a
MetaCyc:
RXN-11471
SABIO-RK:
15076
|
|
|
|
cholic_acid + NAD+ <=> H+ + NADH + 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic_acid
|
1.1.1.159
7alpha-hydroxysteroid dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
–
|
| |
BRENDA:
BR29224
KEGG:
R02792
MetaCyc:
7-ALPHA-HYDROXYSTEROID-DEH-RXN
SABIO-RK:
2666
|
|
|
|
ursocholate + NADP+ <=> 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic_acid + NADPH + H+
|
1.1.1.159
7alpha-hydroxysteroid dehydrogenase
1.1.1.201
7beta-hydroxysteroid dehydrogenase (NADP+)
|
–
–
|
| |
BRENDA:
BS187676;
BS450975
MetaCyc:
RXN-11470
SABIO-RK:
9876
|
|
|
|
cholic_acid + NADP+ <=> H+ + NADPH + 12-ketochenodeoxycholic_acid
|
1.1.1.176
12alpha-hydroxysteroid dehydrogenase
|
–
|
| |
BRENDA:
BR33657
KEGG:
R02793
MetaCyc:
1.1.1.176-RXN
SABIO-RK:
2667
|
|
